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Dr Samantha de Silva, University of Oxford - £24,930

Establishing the link between the apolipoprotein E (APOE) gene and lipid (fat) metabolism and learning what effect this has on the development of AMD.

Professor Susan Downes, Oxford University - £21,380

This project aims to identify the gene that causes some people who are prescribed hydroxychloroquine (HCQ) to develop retinopathy after long term use.

The importance of research into macular disease

Research into macular disease is underfunded in the UK. However, we see first-hand how important research can be for those with macular conditions. Every day we hear of the hope and faith our members have in the research we fund, and in all the research that goes on in the field.

As a member of the Association of Medical Research Charities (AMRC) we have to follow a number of research policies. These policies aim to ensure the best quality research is funded, and to support the research and patient communities, to drive forward positive change.

The Macular Society supports the principle of using animals in research when it is necessary to advance understanding of health and disease and to develop new treatments. This research only takes place where there is no alternative available.

1. General

a. This policy relates to the Research Committee, its Chair and other members.

• Membership of the Research Committee will be for a minimum of three years.
• Membership can be renewed for up to a further three years, by mutual agreement with the Chair of the Committee.
• All members of the Research Committee should be rotated off after six years of service.
• Individuals can re-join the committee after a three year gap.
• Membership will be staggered to ensure continuity of the Research Committee and a clear plan for membership rotation will be developed and maintained.

In order to ensure independent decision making, no more than two Macular Society trustees will sit on the Research Committee at any one time.

The Macular Society believes that stem cell research has the potential to bring great benefit to people with macular conditions. It therefore supports the use of all types of stem cells including embryonic, adult and induced pluripotent stem cells.

We will consider applications for clinical or laboratory-based research projects which can positively impact people with macular disease. This may include research into causes and prevention, early detection, treatments or improving quality of life.

The research grant terms and conditions are available for download below.